Poxel (Group)

Poxel is a dynamic biopharmaceutical company that uses its extensive expertise in developing innovative drugs for metabolic diseases, with a focus on type 2 diabetes and non-alcoholic steatohepatitis (NASH). In its mid-to-late stage pipeline, the Company is currently advancing three drug candidates as well as earlier-stage opportunities. Imeglimin, Poxel’s first-in-class lead product, targets mitochondrial dysfunction. Together, with its partner Sumitomo Dainippon Pharma, Poxel is conducting the Phase 3 Trials of IMeglimin for Efficacy and Safety (TIMES) program for the treatment of type 2 diabetes in Japan. Poxel also established a partnership with Roivant Sciences for Imeglimin’s development and commercialization in countries outside of the partnership with Sumitomo Dainippon Pharma, including the U.S. and Europe. PXL770, a first-in-class direct adenosine monophosphate-activated protein kinase (AMPK) activator, is in a Phase 2a proof-of-concept program for the treatment of NASH. PXL770 could also have the potential to treat additional metabolic diseases. PXL065 (deuterium-stabilized R-pioglitazone), a mitochondrial pyruvate carrier (MPC) inhibitor, is in Phase 1 clinical testing and being developed for the treatment of NASH. Poxel also has additional earlier-stage programs targeting metabolic, specialty and rare diseases. The Company intends to generate further growth through strategic partnerships and pipeline development. Listed on Euronext Paris, Poxel is headquartered in Lyon, France, and has subsidiaries in Boston, MA, and Tokyo, Japan. *

	Start	2009-03-11 splitoff
	Predecessor	Merck Serono (division of Merck KGaA)
	Industry	imeglimin
	Person	Kuhn, Thomas (Poxel 200904– CEO)
	Person 2	Malgouyres, Pascale (Poxel 200904– Business Development Director)

	Region	Lyon
	Country	France

Basic data	Employees	B: 11 to 50 (2014-11-08)
	Currency	EUR
	Cash	42,400,000 (2015-12-31)

		* Document for »About Section«: Poxel S.A.. (11/5/19). "Press Release: Poxel Obtains Additional Funding to Advance Pipeline Programs. Financing of up to EUR 30 Million through a Bond Loan with IPF Partners". Lyon.

		Record changed: 2024-02-12

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