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Organisation › Details

Apeiron Biologics Forschungs- und Entwicklungs GmbH

Apeiron is a mainly privately financed biotech company based in Vienna, Austria, developing immunologic and biologic therapies against cancer. Its portfolio consists of five clinical projects and some preclinical approaches. Its lead project, APN311, is currently being investigated in high-risk neuroblastoma, together with the internationally active SIOPEN study group, with more than 600 patients having received treatment to date. Apeiron's project APN301 is an anti-GD2 antibody-IL2 fusion protein which is currently in a phase II trial in the US and Canada in neuroblastoma and in a separate trial in melanoma. The recombinant human Angiotensin Converting Enzyme 2 (GSK2586881, formerly APN01) was developed by Apeiron until end of Phase I, licensed to GlaxoSmithKline (GSK) in 2010 and is presently being investigated by GSK in an ongoing phase II study in Acute Lung Injury. Furthermore, a program is ongoing to develop therapies to selectively boost the immune system to efficiently combat cancer (APN401: individualized cellular therapy; APN411: low molecular weight compound, in collaboration with Evotec). APN201 (human Superoxide Dismutase) is pursued to cope with oxidative stress and associated inflammation. *


Period Start 2005-09-01 start
Period End 2010-02-04 renamed before
  Group Apeiron (Group)
  Today Apeiron Biologics AG
  Predecessor IMBA – Institute of Molecular Biotechnology GmbH
  Successor Apeiron Biologics AG
Product Industry BIOTECH
Person Person Penninger, Josef (IMBA + Uni Toronto + Uni Wien 200502)
Region Region Wien (Vienna)
  Country Austria
  Street 59 Brunner Str.
  City 1230 Wien
  Tel +43-1-865-6577
    Address record changed: 2008-12-15
Basic data Employees A: 1 to 10 (2008-02-11)
    * Document for �About Section�: Apeiron Biologics AG. (1/9/14). "Press Release: Apeiron Signs Regional License Agreements for the Commercialization of Its Neuroblastoma Therapy". Vienna.
Record changed: 2017-04-01


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