Picture ConsulTech GmbH Berlin Grant Application and Coordination 650x80px
Document › Details

Hookipa Biotech AG. (10/17/16). "Press Release: Hookipa Secures EUR 4.16 Million Additional Grant Support from the Austrian Research Promotion Agency (FFG) to Develop Arenavirus Vector-based Cancer Immunotherapies". Vienna.

Region Region Austria
Organisations Organisation Hookipa Biotech AG
  Group Hookipa (Group)
  Organisation 2 Österreichische Forschungsförderungsgesellschaft mbH (FFG)
  Group Austria (govt)
Products Product HB-201 (Hookipa)
  Product 2 business development (state/region)
Index term Index term Hookipa–Austria (govt): grant, 201610 5th FFG grant €4.16m to develop arenavirus vector-based cancer immunotherapies
Persons Person Aldag, Jörn (Hookipa Biotech 201606– CEO before Uniqure/AMT + Evotec + MAN GHH)
  Person 2 Charles, Susan (Sue) (Instinctif 201611 Manaing Partner Life Sciences before College Group + Northbank + HCC De Facto)

Hookipa Biotech AG, a biotech company pioneering a new class of immunotherapeutics and vaccines based on its proprietary arenavirus vector platforms, today announces the award of a fifth major grant from the Austrian Research Promotion Agency (Forschungs-Förderungs-Gesellschaft, FFG), the leading public funding agency for translational research in Austria.

A EUR 4.16 million grant has been awarded for the second year of a multi-year research and development project. The grant will be used to further substantiate the broad applicability of Hookipa’s arenaviral vector technologies for the development of innovative cancer immunotherapies and to progress the development of Hookipa’s lead oncology product HB201 for the treatment of HPV (human papilloma virus)-associated head and neck cancer.

HB201 is based on Hookipa’s highly potent arenavirus vector platform, stimulating both potent B-cell and CD8+ T-cell immune responses. HB201 is designed to raise immune responses against the E6 and E7 oncogenes of HPV, a known risk factor for head & neck squamous cell cancers1. By inducing strong and sustained cytotoxic T cells, HB201 aims at the eradication of HPV infected or transformed cells from the body. Unlike products based on other viral vectors, HB201 can be applied repeatedly in order to boost the immune system.

Joern Aldag, CEO of Hookipa commented, “After having successfully started a clinical phase 1 study for our Cytomegalovirus (CMV) vaccine candidate earlier this year, we are now actively working towards expanding the use of our technologies into the field of immuno-oncology. FFG´s steady support of this project will help us to accelerate development of urgently needed cancer therapies”.

- ENDS –

About Hookipa Biotech

Hookipa Biotech is an immunotherapy company developing next-generation cancer immune therapeutics and vaccines based on the company´s proprietary arenavirus vector platforms, Vaxwave® and TheraT®. To date, Hookipa has raised EUR 11.5 million in non-dilutive funds and EUR 27 million equity investment from internationally renowned venture capital investors including Sofinnova Partners, Forbion Capital Partners, Boehringer Ingelheim Venture Fund, Takeda Ventures and BioMedPartners. Additional information on Hookipa is available at

About Vaxwave®

Hookipa’s broadly enabling Vaxwave® technology platform is based on replication-defective lymphocytic choriomeningitis virus vectors that allow induction of strong humoral and cellular immune responses to viral, bacterial and tumor antigens. Strong therapeutic efficacy data have been generated in various pre-clinical models. One of the most distinguishing features of this vector platform is its homologous prime-boosting capacity, allowing Vaxwave® based immunotherapy to be applied repeatedly to boost the immune system and generate potent CD8+ T cell responses against targeted antigens. Vaxwave® is patent-protected by issued patents and patent applications worldwide. Hookipa has a phase 1 clinical trial in CMV ongoing using its Vaxwave® platform.

About TheraT®

Hookipa´s TheraT® technology is a novel, stably attenuated and replication-competent viral vector platform capable of inducing tumor antigen-specific effector CD8+ T cells of magnitude and functionality exceeding that of other viral vector platforms. TheraT® has successfully been validated as an immunotherapy in various preclinical tumor models, using different categories of tumor associated antigens ranging from viral genes, differentiation antigens to cancer germline genes. The unique immunostimulatory properties and expected favorable safety profile in humans make TheraT® a very promising cancer immunotherapy platform.


1. National Cancer Intelligence Network (NCIN) Data Briefing: Potentially HPV-related head and neck cancers

Issued for and on behalf Hookipa Biotech AG by Instinctif Partners.

For further information please contact:

At the Company
Joern Aldag
Chief Executive Officer
Hookipa Biotech AG

Media enquiries
Sue Charles/ Daniel Gooch/ Alex Bannister
Instinctif Partners
+44 (0) 20 7866 7905

Record changed: 2016-11-13


Picture [LSUS] – The Business Web Portal 650x65px

More documents for Hookipa (Group)

To subscribe to our free, monthly newsletter for the European life sciences, please send an e-mail to and simply fill the subject line with the word »LSE Newsletter«

To get even more information, please take a look at our [gs] professional services offering and read the gene-sensor Product Flyer [PDF file]

Please visit also our web portals for the European life sciences and the worldwide mass spectrometry industry at (European life sciences) and (worldwide mass spectrometry)

Please visit also our web portals for the life sciences in German-speaking Europe (DE, AT & CH) and the worldwide mass spectrometry industry at (life sciences in German-speaking Europe) and (worldwide mass spectrometry)


Picture Kentro Design Corporate and Web Design Berlin 650x65px

» top