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Scienion AG. (6/22/15). "Press Release: Scienion Introduces a Paradigm Shift in Transmission Electron Microscopy". Berlin.

Organisations Organisation Scienion AG
  Group Scienion (Group)
  Organisation 2 University of California, San Diego (UCSD)
  Group University of California (System)
Products Product sciTEM system
  Product 2 transmission electron microscope (TEM)
Index term Index term Univ California–Scienion: automated liquid handling, 201506 supply existent Gianneschi Group at UCSD is early user of sciTEM system
Persons Person Gianneschi, Nathan C. (Univ California 201506 Dept of Chemistry + Biochemistry at UCSD)
  Person 2 Eickhoff, Holger (Scienion 200012–201008– CEO + co-founder)

SCIENION a leading global provider of ultra-low volume precision liquid handling systems, today announced that it is launching a new instrument, named sciTEM, enabling high-throughput and innovative SEM/TEM.

Based on SCIENION's core competencies and years of experience in ultra-low volume liquid dispensing, assay miniaturization, and microarray manufacturing, the sciTEM was specifically developed to deposit multiple different samples onto a single SEM/TEM support. This results in a tremendous increase in the number of samples that can be analyzed per unit time. Beyond reducing the wear and tear on the microscope’s vacuum components, it truly enables high-throughput TEM. This new usage mode will undoubtedly lead to experiments that could not be realized to date, due to limited access to TEM time, and ensuing high costs.

One of the early applications includes the analysis of nanoparticles. In a nanoparticle industrial production environment, good QC necessitates the analysis of a large number of samples, not only from different batches but also from different time points. Placing multiple samples on a single grid immediately cuts down on the amount of TEM time required. The usage cost saving in itself gives rise to a very high return on investment (ROI).

In addition, it can be used to fill micro-wells to perform in-situ TEM. Liquid Cell Transmission Electron Microscopy (LCTEM) is bringing about a paradigm shift in the analysis of nanomaterials in solution. Dr. Gianneschi’s group was the first to use the sciTEM to load LCTEM cells. "It was an absolute pleasure to work with the sciTEM instrument for LCTEM. The set-up of the instrument was quick and easy and we were able to start collecting excellent imaging results immediately. The sciTEM has already had a significant impact on our LCTEM research and we are looking forward to continued work with the team at SCIENION.” said Dr. Nathan C. Gianneschi (Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California, USA).

"As the leading provider of microarray-based services for a wide variety of applications, we remain committed to our customers in providing the highest quality of products and services in this market," said Holger Eickhoff, SCIENION CEO. "With the sciTEM, we enter the Material Science market and intend to establish the same great reputation we have earned in the Life Science and Diagnostics markets."


SCIENION AG and its US subsidiary SCIENION US, Inc. provide systems and services for the contact-free printing of biological and chemical agents for diagnostics, pharmaceutics, veterinary, plant and food analytics and research. Addressing the dynamically increasing needs for miniaturization and multiplex analyses, SCIENION offers a unique technology portfolio that has been continuously expanded over one decade. SCIENION provides flexible solutions for research and development, wherein solutions for production purposes are customized. Systems and software are characterized by their versatility, precision and robustness. The company is a renowned specialist for ultra-low volume liquid handling, particularly for the handling of precious and sensitive compounds of biological or chemical origin. SCIENION’s dispensers allow for contact-free and precise drop spotting in the pico- to micro-liter range and are optimally suited for microarray based analytics – such as for tests with DNA, oligonucleotides, peptides, proteins, antibodies, glycans or for dispensing cells onto various substrates. The company operates from two sites in Germany, Dortmund and Berlin, and has a subsidiary in New Jersey, USA.


Almut Gebhard
Otto-Hahn-Str. 15
D-44227 Dortmund
Phone +49 (0)30 - 6392 1700
Fax +49 (0)30 - 6392 1701

Record changed: 2017-04-02


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